Multiple system atrophy and autonomic disorders

What are multiple system atrophy and autonomic disorders?

Multiple system atrophy is a progressive neurodegenerative disorder caused by abnormal accumulation of alpha synuclein proteins in the brain. It is similar to Parkinson’s disease and is characterized by rigidity, tremor, slowness of movement and instability. It is also associated with autonomic nervous system problems such as low blood pressure and sensation of light headedness, urinary incontinence, and lower leg swelling. Some patients also have abnormal coordination. It does not typically respond well to medications used to treat Parkinson’s disease, but there are ways to help manage symptoms such as providing supportive medications and therapies.

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