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Guilherme da Silva Mazzini, MD

Specialty
Weight Loss Surgery
Bariatric Surgery
Gastrointestinal Surgery
General Surgery
Department
Surgery

Locations

Stony Point 9109

9109 Stony Point Drive
Richmond, VA 23235
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Short Pump Pavilion

11958 West Broad Street
Henrico, VA 23233
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Tappahannock Pavilion A

659 Hospital Road
Tappahannock, VA 22560
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VCU Health Tappahannock Hospital

618 Hospital Road
Tappahannock, VA 22560
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Adult Outpatient Pavilion

1001 E. Leigh Street
Richmond, VA 23219
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Education

Medical School

Federal University of Rio Grande do Sul

Residency

General Surgery, Hospital de Clinicas de Porto Alegre

Residency

Gastrointestinal Surgery, Hospital de Clinicas de Porto Alegre

Fellowship

Advanced Gastrointestinal Minimally Invasive Surgery, Bariatric and Foregut Surgery, Virginia Commonwealth University


Biography

Forging the future of weight loss surgery with trust

Guilherme da Silva Mazzini, M.D., says surgical care is his life’s calling – and since 2011, he has played a pivotal role in patients attaining a new lease on life.

As a specialist in bariatric surgery at the VCU Health Surgical Weight Loss Center, Mazzini says the team is at the forefront of the field – one which energizes him every day.

“At the end of the day, all we want is to improve patients’ lives. The feeling that I had a positive impact in someone’s life is priceless,” Mazzini says.

For Mazzini, actively partnering with patients on their surgical journey is paramount. This means forming a relationship grounded in trust as well as providing the space for patients – and their families – to have all their questions answered and concerns addressed well before heading to the OR.

“The patient-surgeon relationship is unique because the patient will be under anesthesia while we do our job. It takes a lot of trust to let that happen. My main focus is to ensure my patients are totally comfortable with their treatment plan, all questions answered, so they come completely trustful for their surgery,” Mazzini says.

At the surgical Weight Loss Center, Mazzini works alongside a multidisciplinary team of specialists, therapists and consultants who support patients’ physical, nutritional and emotional well-being and success before, during and after surgery.

Mazzini performs minimally invasive weight loss surgery as well as endoscopic procedures, including gastric bypass, sleeve gastrectomy, and conversions. He also specializes in surgery of the esophagus and stomach, which includes surgical treatment of hiatal hernias, gastroesophageal reflux disease (GERD), gastroparesis, paraesophageal hernias and achalasia. He performs general surgery that includes gallbladder removal and hernia repairs.

With a dedication to exceptional surgical care and cutting-edge procedures, Mazzini emphasizes that it's the patient-centered approach that truly distinguishes him and the VCU team.

“Our specialty is constantly evolving, with more advanced and less invasive procedures developing every day. However, not always the newest treatment is the best for all patients. My challenge is to adopt the most innovative techniques keeping patients’ interest as our main goal. That’s what we call practice of evidence-based medicine,” Mazzini says.

Beyond patient care, he is a passionate clinical researcher and educator, eager for both colleagues and patients to recognize VCU's pioneering role in leading the charge for tomorrow.

“We’re combining excellent health care with a strong academic program that will set the knowledge basis for the development of new treatments and technologies,” he says.

“I’m confident we’re building the future of obesity medicine at VCU.”

Advice to Patients

“Your relationship with your doctor needs to be built with trust. No matter how renowned your doctor is, you will have to trust them with your life. Do your research, choose the best doctor, but make sure you can look him or her in the eye and trust they care about you.”

Research Interests

The impact of bariatric surgery on improving diabetes and other conditions even prior to losing weight. Better understanding this powerful “metabolic effect” will allow care teams to potentially develop new treatments without the need for surgery, which would “benefit hundreds of millions of patients around the world,” Mazzini says.


Clinical Interests

Bariatric/Weight Loss Surgery, Minimally Invasive Surgery, General Surgery, Esophageal/Gastric Surgery, Foregut Surgery, Hernia Surgery

Ratings & Reviews

Overall Rating
Rated 4.8 out of 5 stars based on 40 ratings and 7 comments.

Learn More About the Press Ganey Surveychevron right

Dr Mazzini listened carefully to all my concerns and showed great compassion. He also explained to me some things that my previous specialist and GP did not ever take the time to explain. I am very confident in the care I am receiving.
April 2026
Good.
April 2026
Dr. Mazzini was very professional, very caring, sympathetic for the pain that I was experiencing well mannered gentleman.
July 2025
Had a great experience. Took ample time with me. Presented my health care options & expectations.
June 2025
Have never had such a positive experience. He listened intently - showed me X-rays, etc. that was causing my problems, and was one of the most pleasant and caring doctors I've ever had. I hope this evaluation is shared with him.
May 2025
This was my initial meeting with this provider. I hope he's the one assigned to do my surgeries. He listen and explained everything in a professional, friendly & concerned manner. Instead of rushing to get me to sign my consent for surgery, he listened to my concern and recommended I be cleared with cardiology before the surgery. That meant a lot to me!
September 2024
I appreciate the Drs complete focus & care while with me.
August 2024