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• In 1957, Dr Hume performed the 1st Identical Twin
Renal Transplant at MCV
• Under Dr Hume’s guidance, the Kidney Transplant
Program officially began in 1962; Virginia’s first human
renal allograft was performed at MCV.
• August, 1962, the first living-related donor kidney
transplant was performed;
• October 1962; the first cadaver kidney transplant
took place. Although 1962 is designated as the formal starting
point for the kidney program, it should be noted that Dr.
Hume performed a kidney transplant between twins involving
a living donor in 1957.
• 1962 also marked the opening of MCV Hospitals’
Clinical Transplant Center (CTC), which remains the oldest
unit of it’s kind in the United States;
• In 1963, the first “second” human renal
transplant (retransplant) was performed at MCV;
• In 1964, the Clinical Transplant Center (9 beds) and
self-care unit (15 beds) opened at MCV in the West Hospital;
in 1990 it moved to its current location in the North Hospital
as the Hume-Lee Transplant Unit.
• In 1964, the first “xenotransplant” in
Virginia with successful function of the chimpanzee kidney
into a human was performed at MCV;
• In 1965, MCV’s Tissue Typing Laboratory opened
– one of the first of its kind in the world;
• In 1966, Hyperacute rejection described in kidney
transplantation due to preformed antibody was first characterized
at MCV in the world and this established the need for immunologic
typing for successful transplantation;
• In 1966, the world’s first baby was born to
a mother with renal allograft that was performed at MCV;
• In 1967, Drs. Hume and Lee at MCV showed clinical
relationship of kidney allograft rejection and histocompatibility
matching (tissue typing).
• In 1967, the world’s first experience of baboon
to human cross perfusion for hepatic coma in 6 patients reported
by MCV; 2 of the 6 patients awoke from the coma;
• In 1968, Dr. Hume performed the first liver transplant
and the first long term MCV liver transplant recipient with
1-year survival was reported;
• In 1968, MCV established one of the first Transplant
Surgical Training Programs in the USA, which was approved
continuously by the American Society of Transplant Surgeons
since that group’s inception in 1974. Over 45 transplant
surgeons have been trained at MCV in the past 30 years;
• In 1969, MCV Hospitals and Duke University collaborated
with six other regional medical centers to establish the Southeastern
Organ Procurement Foundation (SEOPF), an organization that
became the nation’s first computerized donor-recipient-matching
system with a grant from NIH and began sharing kidneys between
centers in Virginia, North Carolina, Georgia, and Washington
D.C. for the first time in the world. The State Police and
Air Force assisted with transport;
• In 1968, Virginia’s first human heart transplant
was performed successfully at MCV by Dr. Richard R. Lower;
• In 1972, the “Tucker Trial” resulted from
1968 human heart transplant. This landmark case was presided
over by Judge A.C. Compton, and plaintiff’s lawyer was
Douglas Wilder. The case against MCV surgeons for using another
man’s beating heart for transplant was dismissed. The
case defined for the world the concept of “brain death”
as the modern definition of death;
• In 1972, Dr. Hume and MCV sponsored the world’s
First International Symposium on Clinical Organ Transplantation,
held in Richmond, Virginia;
• In 1973, following Dr. Hume’s untimely death
Dr. H. M. Lee became Chief of Transplantation at the Medical
College of Virginia – a position he held until 1994.
• In 1977, the first long distance cadaver heart procurement
of a heart from Indianapolis to MCV was a successful outcome.
This defined “National Organ Sharing” which has
continued to thrive under UNOS and SEOPF;
• In 1984, the MCV Liver Transplant Program was reactivated
under the guidance of Dr. H. M. Lee, with availability of
new immunosuppression and improved results;
• From 1984-1985, Dr. H.M. Lee, Chairman of MCV Transplant
Program became President of the American Society of Transplant
Surgeons (ASTS) and pushed the signing of the National Organ
Transplant Act into federal law. ASTS President Lee’s
term establishes rigorous ethical standards for transplant
candidate listing and prioritization, transplantation of “foreign
nationals,” and transplant surgeons minimum qualifications;
• In 1986, MCV Hospitals performed the state’s
first heart-lung transplant;
• In 1987, the first Bone Marrow Transplant Program
was established at MCV Hospitals under the direction of Dr.
Craig Howe;
• In 1988, the first bone marrow transplant was performed;
• In 1991, Virginia’s first “reduced size”
(segmental) pediatric orthotopic liver transplantation performed
at MCV is successful;
• In 1992, Virginia’s first adult segmental orthotopic
liver transplantation performed at MCV is successful;
• In 1993, the world’ first human liver cell (cryopreserved)
transplantation was performed in a patient with fulminate
liver failure at MCV, is successful in sustaining life as
a bridge to whole organ transplantation. MCV Transplant program
becomes world leader in hepatocyte transplantation;
• In 1993, the whole organ pancreas transplant program
began at MCV. MCV also sponsored The Third Biennial National
Conference on Psychosocial and Ethical Issues in Organ Transplantation;
• In 1998, Virginia’s first living related donor
segmental orthotopic liver transplant was performed at MCV
and was successful in saving the life of a 2 year old girl.
• Between 1998 and present time, MCVH Transplant Program
at VCUHS has become world leader in pioneering living donor,
adult-adult right lobe liver transplantation with over 60
cases performed with excellent clinical success for recipients
and safety for donors. We were recently recognized in US News
and World Report, July 23, 2001 issue, as the second busiest
living donor liver transplant program in the USA.
• In September, 2000, the transplant program initiated our laparoscopic donor nephrectomy program, which offers an alternative surgical option to our kidney donors.
• In July 2001, Virginia’s first Vascular Access
Program was developed under the direction of Marc P. Posner
MD, Professor and Chairman of the Division of Transplantation
Surgery.
• In July, 2001, the transplant team performed the first pancreas after kidney transplant.
• On March 12, 2002, the transplant center was re-designated and given the official honor of “The Hume-Lee Transplant Center by the Board of the VCU Health System.
• In 2002, Robert A Fisher MD, Director of the Liver Transplantation Program was appointed Regional Counselor for Region 11 by UNOS.
• In 2003, the transplant unit expanded to a 27 bed inpatient unit, including a 4 bed intensive care unit. This unit is one of the largest on the East Coast.
• In August, 2003, the kidney transplant program initiated the desensitization protocol, to reduce antibody levels in recipients that are difficult to transplant.
• In summer, 2004, the transplant program performed the first paired donor kidney exchange, one of twenty seven performed in the country for 2004.
• In Fall, 2004, the transplant program initiated the living/deceased donor exchange for kidney transplant recipients. There were only thirteen of these types of transplants reported in the county for 2004. We are proud to be included as one of the centers offering this program.
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