Valeria Mas

Transplant Clinic, Gateway Building
Room 7-229
Phone number: (804) 628-0960
E-mail: vrmas@hsc.vcu.edu

CITIZENSHIP:

Argentine (I-140 Outstanding Professor or Researcher approved)
I485, Permanent Residence EAC0505552965

EMPLOYMENT HISTORY:

2003- Assistant Professor
Director of Research Molecular Transplant Laboratory
Department of Surgery
Department of Pathology
Division of Transplantation
Virginia Commonwealth University
Richmond, VA 23298-0248
Phone: (804) 628-0960

2000-2003 Post-doctoral Fellow
Molecular Diagnostics, MCV-VCU
Clinical Support Center 247
403 North 13th Street
P.O. Box 980248
Richmond, VA 23298-0248
Phone: (804) 828-9564 ext. 124
Fax: (804) 225-4738

1994-2000 Staff of the Division of Histocompatibility and Molecular Diagnostics
Department of Pathology, Hospital Privado
Catholic University of Córdoba
Naciones Unidas 346
5016 - Córdoba
ARGENTINA

1995-2000 Director Molecular Diagnostics Laboratory
Division of Molecular Diagnosis
Foundation for the Progress of Medicine
Córdoba, Argentina.

1999-2000 Director Immunology Laboratory
Department of Pathology
Hospital Privado
Catholic University of Córdoba
Córdoba, Argentina.

UNDERGRADUATE & GRADUATE EDUCATION:

1992 National University of Córdoba, Córdoba, Argentina.
School of General Chemistry
MS in Clinical Biochemistry

National University of Córdoba
1997 Córdoba, Argentina.
MS in Immunology


2002 Ph.D. in Biochemistry
National University of San Luis
San Luis, Argentina.
November 2000

HONORS & AWARDS:

American Association Clinical Chemistry student travel grant award. Philadelpha, PA, July 2003.

Young Investigator Award, Association for Molecular Pathology. Philadelphia, PA, November 2001.

Best Clinical Research Project in Transplantation Award, 6th Meeting of Argentine Society of Transplantation. Argentine, November 2001.

Young Investigator Award, 6th Meeting of Argentine Society of Transplantation, Argentine, November 2001.

Young Investigator Award, Argentine Society of Clinical Investigation, Argentine November 1999.

Young Investigator Award, Argentine Society of Internal Medicine, Argentine, December 1998.

MEETINGS AND COURSES:

April 22-25, 1998 Member of the Organizing Committee
"Molecular Biology and Clinical Diagnosis"
Córdoba, Argentina.

August, 1998 Member of the Organizing Committee
"Actualization in Immunology "
National University of Córdoba.
Córdoba, Argentina.

April 13-17, 1999 Member of the Organizing Committee and Instructor of the course: "Molecular Biology and Biomedicine"
Córdoba, Argentina.

April 2002-

ACADEMIC POSITIONS:

1991-1992 Junior Scholarship. Central Clinical Laboratory
University Hospital, School of Medicine,
National University of Córdoba, Argentina.

1991-1992 Teaching Assistant. Department of Clinical Chemistry. School of General Chemistry,
National University of Córdoba, Argentina.

1992-1993 Senior Scholarship. Central Clinical Laboratory
University Hospital, School of Medicine,
National University of Córdoba, Argentina.

1995-1997 Fellow in Immunology
Department of Immunology, School of General Chemistry. National University of Córdoba, Argentina.

TEACHING EXPERIENCE:

1997 - 2000 Faculty in Immunology
Internal Medicine Residency Program
Hospital Privado of Córdoba.
Córdoba, Argentina.

1997-2000 Faculty in Molecular Biology Graduate Program
Foundation for the Progress of Medicine
Córdoba, Argentina.

July 1999-July 2000 Thesis Advisor
Roggio Foundation, Cordoba, Argentina.

Sept 1999-Sept 2000 Thesis Advisor of a student of Biology
National University of Córdoba,
Cordoba, Argentina.

1999-2001 Instructor in Immunology
Department of Immunology, School of General Chemistry. National University of Córdoba, Argentina.

WORKSHOPS & CONFERENCES:

November 1995. Infectious Diseases Society of Córdoba: Utility of PCR for diagnosis in immunosuppressed patients. Hospital Rawson, Córdoba. Lecturer.

April 1996. Hepatology Society: Immunology markers in viral hepatitis. Central Hospital of Río Cuarto, Córdoba. Lecturer.

April 1997. Grand Round of Medicine: Clinical utility of molecular diagnosis of Mycobacterium tuberculosis. Sanatorio Allende, Córdoba. Lecturer.

July 1997. Post-graduate Annual Course of Dermatology: Molecular techniques in skin diseases. Catholic University of Córdoba. Lecturer.

April 1997. Post-graduate Annual Course of Infectious Diseases: PCR reaction and modifications in the diagnosis of infection diseases in transplant patients. Hospital Nacional de Clínicas, National University of Córdoba, Córdoba. Lecturer.

August 1997. Nephrology Ground Rounds: Papooses. Hospital Privado de Córdoba. Córdoba, Co-director and Lecturer.

August 1997. Human Cytomegalovirus (HCMV) and kidney transplant. Annual Meeting. Hospital Privado de Córdoba, Córdoba. Lecturer.

July 1997. “BRCA 1 and BRCA 2 genes: future impact of molecular diagnosis. Foundation for the Progress of Medicine, Córdoba. Coordinator.

October 1997. Microbiology Society of Córdoba: The role of PCR in the diagnosis of infectious diseases. Catholic University of Córdoba, Continuing Medical Education Program, Córdoba. Lecturer.

May 1998. Continuing Medical Education Program for Graduate Students and Fellows Introduction to Molecular Biology. Hospital Privado, Córdoba. Coordinator.

May 1998. Continuing Medical Education Program of Graduate Students and Fellows Diagnostic of Factor V Leiden using PCR-RFLP. Hospital Privado, Córdoba. Lecturer.

May 1998. Continuing Medical Education Program of Graduate Students and Fellows. Molecular diagnosis of skins T-cell lymphoma using gamma-delta gene rearrangements. Hospital Privado, Córdoba. Lecturer.

May 1998. Molecular Pathology Workshop. Hospital Privado, Córdoba. Co-chair, laboratory instructor and lecturer.

September 1998. Córdoba Pathology Society. Biochemistry Meeting. Hepatitis C Virus (HCV) infection and autoimmunity. Córdoba. Lecturer

May 1999. Molecular Pathology Workshop. Hospital Privado, Córdoba. Co-chair, laboratory instructor and lecturer.

June 1999. Oncology Meeting: Molecular Oncology Diagnosis. Hospital Privado, Córdoba. Lecturer.

April 2000. National Academy of Medicine: Clinical utility of molecular markers in monitoring of minimal residual disease (MRD) in acute leukemia. Buenos Aires, Argentina. Lecturer.

June 2000. Continuing Medical Education Program of Graduate Students and Fellows: Post-transplant lynphoproliferative disorder (PTLD) in kidney transplant patients. Hospital Privado, Córdoba. Lecturer.

April 2002-present. Molecular Pathology Practicum. Pathology Department. CME category: program for 80 hours. On going two-week monthly workshop. Lecturer.

August-September 2002. Molecular Diagnostics in Clinical Laboratory Sciences,
Advanced Masters Track in the Clinical Laboratory Sciences program. Lectures: Branched DNA Allele-Specific Oligonucleotides (ASO) and reverse blots Strand displacement amplification (SDA) Nucleic acid sequence based amplification (NASBA) Transcription-Mediated Amplification (TMA). Lecturer.

PUBLICATIONS:

1. Mas V. Utility of polymerase chain reaction for diagnosis of human tuberculosis. Experiencia Médica, 1995, Vol XIII Nº 2; pag: 11-13.

2. Albano S; Mas V; Alvarellos T; Giraudo C; Boccardo G. Effect of Isradipine in the “in vitro” lymphocitary proliferation. “Transplantes”, publicación científica de la Sociedad Argentina de Transplantes. 1996,Vol 2 Nº 2.

3. Mas V; Albano S; Boccardo G; Giraudo C; Alvarellos T. Neutrophilic Anticitoplasmic antibodies in renal transplant. “Transplantes”, publicación científica de la Sociedad Argentina de Transplantes. 1997, Vol 3 Nº1.

4. Alvarellos T; Mas V; Albano S; Giraudo C; Massari P; Boccardo G. Detection of cytomegalovirus by polymerase chain reaction in renal transplant. Experiencia Médica. Nov 1997.

5. Albano S; Mas V, Alvarellos T; Lascano A; Campana R; Giraudo C; Boccardo G. Utility of polymerase chain reaction for the detection of HSV I and II in atypic cutaneous lesions in renal transplant patients. Experiencia Médica 1997.

6. Mas V; Alvarellos T; Albano S; Giraudo C; Boccardo G, Garret CT; Ferreira Gonzalez A. Clinical utility of CMV viral load in renal transplant patients. Transplantation 1999; April 15, Vol. 67,Nº 7.

7. Mas V; Sena J; Diller A; Albano S; Giraudo C; Alvarellos T; Massari P; Boccardo G. Intragraft expression of TGF beta 1 by a novel quantitative RT-PCR-ELISA in long lasting kidney receptors. Transplantation 2000, 70(4): 612-6.
8. Mas V; Alvarellos T; Chiurchiu C; Camps D; Massari P; Boccardo G. Hepatitis C Virus (HCV) Infection after renal transplant: viral load and outcome. Transplantation Proceedings 2001, 33(1-2): 1791-3.

9- Mas V, Alvarellos T, Giraudo C, Massari P and de Boccardo G. Intragraft messenger RNA expression of angiotensinogen: relationship with transforming growth factor beta-1 (TGF1) and chronic allograft nephropathy in kidney transplant patients. Transplantation 2002, 74 (5) 718-721.

10- Albano S; Mas V; de Boccardo G; Giraudo C; Massari P; Alvarellos T. Chagas´disease in Kidney Transplant Patients. Transplant Infectious Disease (in review).

11- Mas V, Fisher RA, Maluf D, Wilkinson D, Garret CT, Ferreira-Gonzalez A. Hepatic Artery Thrombosis after Liver Transplantation and Genetic Factors. Prothrombin G20210A Polymorphism. Transplantation 2003;76:247.

12- Mas V, Fisher RA, Maluf DG, Contos M, Shiffman M, Wilkinson DS, Oliveros L, Garrett CT, Ferreira-Gonzalez A. Single Nucleotide Polymorphisms (SNPs) as Predictors of the Outcome after Liver Transplantation. Clinical Genetics 2004; 65: 191-201.

13- Mas V, Maluf D, Thomson M, Ferreira-Gonzalez A, Fisher RA. Engraftment measurement in human liver tissue after liver cell transplantation by Short Tandem Repeats analysis. Cell Transplant. 2004; 13(3):231-6.

14- Mas VR, Maluf DG, Stravitz R, Dumur CI, Clark B, Rodgers C, Ferreira-Gonzalez A, Fisher RA.Hepatocellular carcinoma in HCV-infected patients awaiting liver transplantation: genes involved in tumor progression. Liver Transpl. 2004;10(5):607-20.

15- Mas VR, Alvarellos T, Maluf DG, Ferreira-Gonzalez A, Oliveros L, Maldonado RA, De Boccardo G. Molecular and clinical response to angiotensin II receptor antagonist in kidney transplant patients with chronic allograft nephropathy. Transpl Int. 2004 Oct; 17(9):540-4.

16- Dumur CI, Nasim S, Best AM, Archer KJ, Ladd AC, Mas VR, Wilkinson DS, Garrett CT, Ferreira-Gonzalez A. Evaluation of Quality-Control Criteria for Microarray Gene Expression Analysis. Clin Chem. 2004; 13(3):231-6.

17- Mas V, Maluf G, Archer K, Yanek K, Cotterell A, King A, Gonzalez-Ferreira A, Rodgers C, Fisher RA, Posner M. Study of mRNA Growth Factors in Urinary Cells of Kidney Transplant Recipients as predictors of Chronic Allograft Nephropathy. Transplantation 2005 (in Press)

18- Maluf G, Mas V, Archer K, Yanek K, King A, Gonzalez-Ferreira A, Rodgers C, Fisher RA, Posner M. Apolipoprotein E genotypes as predictors of high-risk group for developing hyperlipidemia in kidney transplant recipients undergoing sirolimus treatment. Transplantation 2005 (in Press)

19- Mas V, Maluf D, Dumur C, Archer K, Yanek K, Jackson-Cook C, Fisher R. Molecular techniques for identifying HCC origin and biology after orthotopic liver transplantation. Diagnostic Molecular Pathology (in Press)

ABSTRACTS:

1. Mas V, Albano S, Alvarellos T, Grosso S, Massari P, Boccardo G. Spontaneous Blastogenesis in patients with chronic rejection. IX Argentine Congress of Nephrology. Villa Carlos Paz, Córdoba. April 1994.

2. Mas V, Ruata I, Cocca H, Orozco F, Alvarellos A. Utility of PCR in Mycobacterium tuberculosis diagnosis. XXI National Meeting of Internal Medicine. Buenos Aires, Argentina. November 1994.

3. Mas V, Agüero S, Alvarellos A, Caeiro F. Neutrophilic Anti-citoplasmatic antibodies in patients with systemic erythematous lupus. Argentine Society of Rheumatology. XXXIII Argentine Congress of Rheumatology. Mendoza, Argentina. November 1994.

4. Mas V, Camps D, De Arteaga J, Alvarellos T. Hepatitis C virus (VHC) infection in dialyzed patients. V National Congress of Medicine. XXII Internal Medicine Congress for Residents. Rosario, Argentina. November 1995.

5. Mas V, Albano S, Boccardo G, Giraudo C, Alvarellos T. Anti-neutrophilic antibodies in renal transplanted patients. 1st meeting of the Transplant Societies of Argentina, Brasil, Chile and Uruguay. X Argentine Transplant Congress. Buenos Aires, Argentina. April 1996.

6. Mas V, Camps D, De Arteaga J, Alvarellos T. Hepatitis C virus (VHC) infection in dialyzed patients. Argentine Congress of Virology. University of Tandil. Tandil, Buenos Aires. April 1996.

7. Albano S, Mas V, Alvarellos T, Giraudo C, Boccardo G. In vitro effect of Isradipine oer the lymphocitary activation. 1st Meeting of the Transplant Societies of Argentina, Brasil, Chile and Uruguay. X Argentine Transplant Congress. Buenos Aires, Argentina. April 1996.

8. Mas V, Alvarellos T, Albano S, Giraudo C, Massari P, Boccardo G. Hepatitis C Virus (VHC) Infection in Kidney Transplant. X Latin-American Congress of Nephrology and Hypertension. Santiago, Chile. September 1996.

9. Mas V, Alvarellos T, Albano S, Giraudo C, Massari P, Boccardo G. Cytomegalovirus (CMV) PCR in Kidney Transplant. X Latin-American Congress of Nephrology and Hypertension. Santiago, Chile. September 1996.

10. Albano S, Mas V, Ruiz-Lascano A, Campana R, Giraudo C, Boccardo G. Utility of PCR in atypical skin lesions from Kidney Transplant Patients. Internal Medicine Congress for Residents. Mar del Plata. November 1996.

11. Mas V, Agüero S, Alvarellos A, Albano S, Alvarellos T, Caeiro F. Importance of the detection of cytomegalovirus in patients with systemic erythematous lupus). Argentine Congress of Rheumatology. Mar del Plata. November 1996.

12. Mas V, Albano S, Alvarellos T, Giraudo C, Boccardo G, Palazzo E. Detection of t (15, 17) in promyelocitic leukemia using RT-PCR. Congreso Nacional de Hematología y Hemostasia. Carlos Paz. October 1997.

13. Agüero S, Albano S, Mas V, Alvarllos T, Alvarellos A, Omelianuk M, Caeiro F. Neutrophilic Anti-citoplasmic antibodies and their association to the specificity PR3 and myeloperoxidasa. Argentine Congress of Rheumatology. Mar del Plata. November 1997.

14. Méndez J, Albertini R, Lascurain P, Mas V, Alvarellos T. PCR and early TB Diagnosis: A General Hospital Experience. VII National Congress of Internal Medicine. Buenos Aires. November 1997.

15. Mas V; Alvarellos T; Albano S; Giraudo C; Boccardo G; Garret CT; Gonzalez A. Clinical Utility of CMV Viral load in Renal Allograft Recipients in Argentina. American Molecular Pathology. San Diego, CA. American Journal Pathology Vol. 151(5), Nov 1997.

16. Albano S; Mas V; de Boccardo G; Giraudo C; Massari P; Alvarellos T. Chagas´disease in Kidney Transplant Patients. ASTP 17 Annual Meeting (poster). Chicago, IL. May 1998.

17. Mas V; Alvarellos T; Albano S; Giraudo C; Boccardo G; Garret CT; Gonzalez-Ferreyra A. CMV Viral Load in Renal Allograft Recipients. ASTP 17 Annual Meeting. Chicago, IL. May 1998.

18. De Arteaga J; Alvarellos T; Mas V; Albano S; Giraudo C; Douthat W; Zárate A; Massari P. PCR of Ascitic or Peritoneal Dialysis Fluid. A Useful Technique in the Diagnosis of Fungal or Mycobacteria Peritonitis. 3rd European Peritoneal Dialysis Meeting. Edinburgh April 5-7, 1998.

19. Mas V, Albano S, Alvarellos T, Giraudo C, Boccardo G. Hepatitis C virus infection in kidney transplant: three years of monitoring. SAIC (Sociedad Argentina de Investigacion Clinica). Mar del Plata, 1998.

20. Mas V, Alvarellos T, Albano S, Giraudo C, Boccardo G. Design and analytic validation of quantitative PCR competitive for human cytomegalovirus. SAIC. Mar del Plata, 1998.

21. Albano S; Mas V; Alvarellos T; Boccardo G; Giraudo C. Analysis of antigens of histocompatibility I using Molecular Biology Methods. SAI (Sociedad Argentina de Inmunología). Mar del Plata. Nov 1998.

22. Mas V; Sena, J; Diller A; Albano S; Giraudo C; Alvarellos T; Massari P; Boccardo G. Quantitation of TGF-beta 1 using a Quantitative Competitive RT-PCR-ELISA in Chronic Graft Nephropathy. XV International Congress of Nephrology. Buenos Aires, May 1999.

23. Mas V; Sena J; Diller A; Albano S; Giraudo C; Alvarellos T; Massari P; Boccardo G. Intragraft expression of TGF-beta 1 by a Novel Quantitative RT-PCR-ELISA in Long Lasting Kidney Receptors. ASTP 18 Annual Meeting. Chicago, IL. May 1999.

24. Mas V; Alvarellos T; Chiurchiu C; Camps D; Massari P; Boccardo G. HCV Infection After Renal Transplant: Viral Load and Outcome. ASTP 19 Annual Meeting. Chicago, IL. May 2000.

25. Mas V; Alvarellos T; Albano S; Chiurchiu C; Giraudo C; Massari P; Boccardo G. Messenger RNA Expression of Angiotensinogen and TGF-b1 in Kidney Transplant Patients. XVIII International Congress of the Transplantation Society. Roma, August 2000.

26. Vettorazi L; Alvarellos T; de Boccardo G, Mas V. Quantitation of EBV viral load in renal transplant patients with Post-Transplant Lymphoproliferative Disorder (PTLD).
Argentine Society of Clinical Research, Mar del Plata, Argentine, November 2000.

27. Mas V, Alvarellos T, Maldonado R, and de Boccardo G, Clinical and Molecular Response to losartan in chronic allograft nephropathy (CAN). Istanbul, May 2001.

28. Mas V, Fisher RA, Contos M, Wilkinson DS, Garrett CT, Ferreira-Gonzalez A.
Pro-Inflammatory, Pro-Fibrotic genotypes in End-Stage Liver Disease (ESLD). Association for Molecular Pathology, Annual Meeting, November 2001, Philadelphia, PA.

29. Mas V, Pandya A, Nance W, Wilkinson DS, Garrett CT, Ferreira-Gonzalez A.
Cost effectiveness a single high-throughput sequencing on ABI 3100 genetic analyzer for detecting mutations in the connexin 26 gene (Cx26). Association for Molecular Pathology, Annual Meeting, November 2001, Philadelphia, PA.

30. O’Grady A, Dumur C, Powers C, Mas V, Garret CT and Ferreira-Gonzalez A. Optimization and Validation of a real-time PCR Assay for t (14:18) quantification in Lymphoma Specimens. The United States and Canadian Academy of Pathology Annual Meeting, Chicago, Ill, USA. February 2002.

31. Mas V, Fisher RA, Maluf D, Contos M, Wilkinson D, Garrett CT, Ferreira- Gonzalez A.
Host Genetic factors as predictive markers of outcome after liver transplantation. ASTP 21 Annual Meeting. Washington DC, USA. May 2002.

32. Mas V, Fisher RA, Maluf D, Contos M, Wilkinson D, Garrett CT, Ferreira- Gonzalez A.
Determination of Pro-Fibrotic, Pro-Inflammatory Genotypes in Pre-transplant liver recipients using SNaPSHOTTM Multiplex Assay. ASTP 21 Annual Meeting. Washington DC, USA. May 2002.

33. Mas V, Epp L, Contos M, Mills S, Shiffman M, Wilkinson D, Garrett CT and Ferreira-Gonzalez A. IFN-alpha Receptor (IFNAR) and IFN-Inducible-MxA Gene Single Nucleotide Polymorphism (SNP) and virological response in patients with chronic Hepatitis C Virus (HCV) treated with IFN. Association for Molecular Pathology, Dallas,TX. November 2002.

34. Mas V, Epp L, Contos M, Mills S, Shiffman M, Wilkinson D, Garrett CT and Ferreira-Gonzalez A. Host Genetic Factors and liver fibrosis in patients with chronic Hepatitis C Virus. Association for Molecular Pathology, Dallas,TX. November 2002.

35. Mas V, Dumur C, Ware J, Wilkinson D, Garrett CT, Ferreira-Gonzalez A. Detection of Loss of Heterozygosity (LOH) in Laser Capture Microdissected (LCM) Prostate Cancer Paraffin-Embedded Tissues using electronic microarrays. Association for Molecular Pathology, Orlando, FL November 2003.

36. Mas V, Maluf D, Stravitz R, Bradly C, Rodgers C, Ferreira-Gonzalez A, Fisher RA. Gene Expression Patterns in Cirrhosis and Hepatocellular Carcinoma (HCC) in HCV-infected Patients awaiting Liver Transplantation. American Transplantation Congress, Boston, May 2004.

MEMBERSHIPS IN PROFESSIONAL ORGANIZATIONS

Transplant Society of Córdoba
Argentina Society of Transplant
Argentine Society of Clinical Research
Association for Molecular Pathology
American Association for Clinical Chemistry

EXTRAMURAL FOUNDING:
Completed Research Support

1. Roggio Foundation: Clinical research Study, Clinical Utility of molecular markers in Minimal Residual Disease (MRD) in patients with acute leukemia. Mas V; Principal Investigator. December 1998-December 2000.

Specific Aim: Clinical Research Trial to Evaluate the Clinical Utility of Molecular Markers (B and T Cell Rearrangements Genes, t (4;11) and t (9;22) chromosomal translocations) as predicting markers of relapse.

2. Nephrology Foundation of Córdoba: Intragraft expression of TGF-1 in kidney transplant patients. Mas V; Principal Investigator. July 1998-July 1999.

Specific Aim: Clinical Research Trial to Evaluate the Clinical Utility of a Novel Quantitative Competitive RT-PCR for Quantitation of mRNA-TGF-1 in Kidney Biopsies of Kidney Recipients. To study the relationship between TGF-1 expression and chronic allograft nephropathy (CAN).

3. Nephrology Foundation of Córdoba: Clinical Research Project: mRNA of angiotensinogen in kidney biopsies of transplant patients: relationship with mRNA of TGF-1 and CAN. Mas V; Principal Investigator. July 1999-July 2000.

Specific Aim: Clinical Research Trial To Study Relationship Among Amounts Of mRNA-AGT, TGF-B1 and Banff Criteria.

4. Nephrology Foundation of Córdoba: Clinical Research Project: Post-transplant Lynphoproliferative Disease in Kidney Transplant Recipients. Mas V; Principal Investigator. July 2000-July 2001.

Specific Aim: Clinical Research Study Where We Quantified Viral Load of Epstein-Barr Virus As Prognostic Marker Of Disease.

5. Nephrology Foundation of Córdoba: Clinical Research Project: Intragraft mRNA levels of angiotensinogen, TGF-b1 and Angiotensin II receptor in Kidney transplant patients with angiotensin II receptor antagonists. Mas V; Principal Investigator. March 2000-May 2001.

Specific Aim: To identify molecular mechanisms involved in the development of fibrosis in chronic allograft nephropathy.

6. Investigation Project CONICET. Linkage analysis of potassium channel KCNA 10 in hypertenses patients. Mas V, Co investigator, March 2000-2002.

Specific Aim: To identify genetic markers associated with hypertension in-patients with family history of Hypertension.

Active Research Support

Wyeth Pilot Project
PI: Daniel Maluf, MD
Date: 10/30/04-10/30/05
Agency: Wyeth Pharmaceuticals, Collegeville, PA.
Title: Apo-lipoprotein genetic polymorphisms as predictors of high-risk group for hyperlipidemia in kidney transplant recipients undergoing sirolimus treatment.
Role: Co-investigator.

MCC Pilot Project
PI: Valeria r Mas, Ph.D. and kellie J Archer, Ph.D.
Date: 08/01/05-07/31/06
Agency: Massey cancer Center Pilot Project Program
Title: Predicting HCC progression using molecular markers in patients awaiting liver transplantation.
Role: Co-PI

Cell 500- ROCHE LABORATORIES INVESTIGATOR INITIATED RESEARCH PROGRAM.
PI: Daniel Maluf, MD, Valeria Mas, Ph.D.
Date: 10/30/05-9/30/07
Agency: ROCHE LABORATORIES INVESTIGATOR INITIATED RESEARCH PROGRAM
Title: New strategies for non-invasive detection of Chronic Allograft Nephropathy.
Role: Co-PI

Pending Founding

RO1 DK069859-01
Genes related to HCC progression in LD and DD Transplant
Co-investigator, effort: 75%
Major goal: The long-range goal of this project is to identify the genetic markers related to the hepatocellular carcinoma (HCC) progression and prognosis in hepatitis C virus (HCV)-infected liver transplant recipients. Genome-wide loss of heterozygosity (LOH) analysis and gene expression profiling will be used as tools for the identification, analysis and association studies.

PAR-04-132- T32 Predoctoral Research Training in Biostatistics Grant.
Co-investigator, effort 10%
Major goal: Training of pre-doctoral biostatistics students to receive rigorous, in-depth training in biostatistics AND some interdisciplinary training in biological sciences.

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